No, not if you know what you're doing. We have had guitarplayernails.com for over twenty years now. We have thousands of guitarists who have used, and are currently using our nails long term with nothing but great results. If you are aware of just a few simple things, you can use artificial nails every day for your entire life with no damage to your natural nails. I personally have applied, and have taken off thousands of artificial nails on my own fingers. I haven't used my real nails in well over twenty years now, and my natural nails are perfectly healthy. One important thing to remember is that your nails are always growing, so there will always be new nail. Fingernails are made from keratin. There are no nerve endings, no pores, and despite what some may believe, fingernails do not need to breathe. So it does not hurt to cover the natural nail with fingernail glue, and whatever material you may prefer; (ping pong balls, nail tips, our nails, etc). And of course, the nail will grow out in just a few weeks and there will always be new nail. When applied correctly, there is no substitute for good artificial nail material applied with fingernail glue. That way the nail becomes part of you, and feels like a really good natural nail. You just can't get the same results by using fingerpicks, Alaska picks, or Rico nails with glue dots; As a temporary solution....fine, but your playing will suffer during this time. (By the way if you like the pre-formed nails like the Rico nails, you don't have to pay $1.50 for each nail. You can get them at retail stores, drug stores etc, for a lot less. We sell them at guitarplayernails.com for less than twenty cents each). Pre-formed nails are not made from the best material for guitar nails; (ABS plastic), but some are better than others. Using silk wrap with pre-formed nails also helps. But there is material out there, that if applied correctly, sounds like great natural nails, is durable, easy to use, has great feel and tone.... and will help your guitar playing immensely.
This is what Eliot Fisk says about our nails at guitarplayernails.com:
"This is a huge revolutionary change for guitar players. I think even you do not realize how big of a revolution this represents. We are now in the realm of bassoon and oboe players with their reeds!!"
Anyway, no matter what kind of artificial nails you use, keep these things in mind.
Always keep the nail sealed. If the nail comes up off the natural nail, glue it back down. Never let the nail fall off on its own. Either leave it on, or take it off.This way you won't get water stuck in between the natural and artificial nail.
Always only apply artificial nails to 3/4 of your natural nail plate at the most. Always leave the back of the nail free of any nail material.
If your natural nail is thin or sensitive, (from removing acrylic nails, or you removed too much natural nail, etc.), always build it up a bit with some brush on nail glue, or any viscous nail glue, so that there is no longer any sensitivity. Then put on a new nail.
Even if fingernail glue dries out your nail, makes it brittle, feels weird etc., it's nothing to worry about, there will always be new nail growing out. Follow the above rules and your natural nails will be fine.
We have a lot more info at guitarplayernails.com that you can use no matter what nails you decide to use. We've learned a lot over the last 25 years or so, much more than I can put down here. Bottom line is you can have great sounding nails any time you want. And when you get a bit of experience, you'll be able to remove an old nail, put on a new nail and be ready to play in 4 or 5 minutes.